Apple is expected to GA macOS 11.3 today, April 20th 2021. We have been advised by SentinelOne an interoperability issue exists with the SentinelOne agent, which will cause the agent to become unresponsive and prevents the ability to upgrade.
SentinelOne is working on a new Mac agent to support macOS 11.3 in a subsequent release.
As always SentinelOne advises not to adopt the latest macOS release until it has been tested and approved.